ST2 and galectin-3 as novel biomarkers for the prediction of future cardiovascular disease risk in preeclampsia

Autor: Nil Atakul, Yıldız Atamer, Şahabettin Selek, Berna Kılıç, Fatmanur Koktasoglu
Přispěvatelé: KÖKTAŞOĞLU, FATMANUR
Rok vydání: 2021
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology. 42:1023-1029
ISSN: 1364-6893
0144-3615
Popis: The aim of this study was to investigate known cardiovascular disease (CVD) risk biomarkers galectin-3 (Gal-3) and human stromelysin-2 (ST2) levels in preeclampsia (PE) and normotensive pregnancies. A case-control study was conducted in a teaching and research hospital. We performed data analysis involving 45 pregnant women with PE and gestational week (GW) matched 35 normotensive pregnant women. The Gal-3 and ST2 levels were determined by using ELISA kit. Gal-3 values did not differ statistically between PE and control groups (535.1 ng/mL vs. 615.2 ng/mL) (p> .05). ST2 value in the PE group was statistically significantly lower than the control group (33.3 pg/mL vs. PE, 54.5 pg/mL, p 34 GW patients (late-onset PE) had statistically significantly lower Gal-3 values than the
Databáze: OpenAIRE