Electrocardiographic findings in a cross-sectional study of human immunodeficiency virus (HIV) patients in Enugu, south-east Nigeria

Autor: B.J.C. Onwubere, BC Anisiuba, EC Ejim, Samuel O Ike, Paschal Njoku
Rok vydání: 2016
Předmět:
Adult
Male
medicine.medical_specialty
Time Factors
Cross-sectional study
Nigeria
HIV Infections
electrocardiogram
030204 cardiovascular system & hematology
Left ventricular hypertrophy
Hospitals
University

Electrocardiography
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Antiretroviral Therapy
Highly Active

Internal medicine
Post-hoc analysis
Prevalence
Humans
Medicine
030212 general & internal medicine
Analysis of Variance
Chi-Square Distribution
human immunodeficiency virus
medicine.diagnostic_test
business.industry
Cardiovascular Topics
Case-control study
virus diseases
Arrhythmias
Cardiac

General Medicine
highly active antiretroviral therapy
medicine.disease
Electrocardiographic Finding
Surgery
Cross-Sectional Studies
Case-Control Studies
Predictive value of tests
Female
abnormalities
Cardiology and Cardiovascular Medicine
business
Chi-squared distribution
Zdroj: Cardiovascular Journal of Africa
ISSN: 1680-0745
1995-1892
DOI: 10.5830/cvja-2016-007
Popis: Summary Background Electrocardiographic (ECG) abnormalities are prevalent in subjects with human immunodeficiency virus (HIV) infection. In this study, three groups of subjects were investigated and the prevalence of ECG abnormalities was analysed. Methods A cross-sectional study was carried out on adults between November 2010 and November 2011 at the University of Nigeria Teaching Hospital, Enugu, Nigeria. One hundred HIV-infected patients on highly active anti-retroviral therapy (HAART), 100 HIV-infected HAART-naïve patients and 100 HIV-negative controls were recruited. Twelve-lead electrocardiograms were done on all subjects. Data were analysed using the chi-squared, Student’s t-, one-way ANOVA and Duncan post hoc tests. Results Left-axis deviation was seen in 15 (16%) of the HIV-positive subjects on HAART, 10 (13.7%) of the HAART-naïve subjects and eight (21%) of the controls (p = 0.265). Eight (11%) subjects with left ventricular hypertrophy (p
Databáze: OpenAIRE