Enhancement, by Two Carboxylic Acid Interferon Inducers, of Resistance Stimulated in Mice by Foot-and-Mouth Disease Vaccine
| Autor: | C. H. Campbell, J. Y. Richmond |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Interferon Inducers
Carboxylic acid Immunology Carboxylic Acids Immunization Secondary Hemolytic Plaque Technique Microbiology Virus Mice Aphthovirus Immunity medicine Animals chemistry.chemical_classification Interferon inducer biology Foot-and-mouth disease Viral Vaccine Viral Vaccines biology.organism_classification medicine.disease Virology Viral Infections Infectious Diseases chemistry Foot-and-Mouth Disease Antibody Formation biology.protein Parasitology Antibody |
| Zdroj: | Infection and Immunity. 7:199-204 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.7.2.199-204.1973 |
| Popis: | Simultaneous injection of divinyl ether-maleic amhydride (DVE/MA) or itaconic-acrylic acid and foot-and-mouth disease virus vaccine enhanced the survival of infant mice to subsequent injections of virus. This enhanced resistance was obtained even with doses of interferon inducers which, when administered alone, failed to protect the mice. There was some increase in serum-neutralizing antibody in mice 7 days after injection of DVE/MA and vaccine, as compared with mice given vaccine alone, but there was no clear connection between antibody level and amount of DVE/MA administered. |
| Databáze: | OpenAIRE |
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