Layer-by-layer coating and chemical cross-linking of multilayer polysaccharides on silica for mixed-mode HPLC application
| Autor: | Zhanying Chu, Weibing Zhang, Xiang Fang, Liqing Wu, Xinhua Dai, Gong Xiaoyun, Rui Zhai, Manman Zhu, Yang Zhao, Jiang You |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Composite number Shell (structure) engineering.material High-performance liquid chromatography Catalysis Chitosan chemistry.chemical_compound Coating Polysaccharides Materials Chemistry Carbohydrate Conformation Particle Size Chromatography High Pressure Liquid Hydrophilic interaction chromatography Layer by layer Metals and Alloys General Chemistry Silicon Dioxide Environmentally friendly Surfaces Coatings and Films Electronic Optical and Magnetic Materials Cross-Linking Reagents Chemical engineering chemistry Ceramics and Composites engineering |
| Zdroj: | Chemical communications (Cambridge, England). 57(96) |
| ISSN: | 1364-548X |
| Popis: | A facile, controllable and environmentally friendly method for fabricating a novel polysaccharide–silica composite stationary phase (SiO2@(HA-CS)12) was developed in this report. Two natural polysaccharides (hyaluronan acid and chitosan) were controllably coated on the silica surface using a layer-by-layer assembly technique, and then the polysaccharide shell was chemically cross-linked to improve the stability. The column efficiency of the SiO2@(HA-CS)12 column reached 74 000 plates per m in HILIC mode and 20 100 plates per m in IEC mode, which indicates great potential for separating polar and charged samples. |
| Databáze: | OpenAIRE |
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