New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research

Autor: Luiz Felipe P. Moreira, Luís Alberto Oliveira Dallan, Noedir Antônio Groppo Stolf, Jackson Brandão Lopes, Pedro de Castro Mendes, Mario Castro Carreiro, Flávia Luana Barbosa Rodrigues
Rok vydání: 2009
Předmět:
Zdroj: Acta Cirúrgica Brasileira v.24 n.2 2009
Acta Cirúrgica Brasileira
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
Acta Cirurgica Brasileira, Volume: 24, Issue: 2, Pages: 82-86, Published: APR 2009
ISSN: 0102-8650
DOI: 10.1590/s0102-86502009000200002
Popis: PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p
Databáze: OpenAIRE