Rhinitis symptoms and quality of life in patients with chronic perennial rhinitis treated with desloratadine
| Autor: | M. C. F. Tong, Henry Chuen Kwong Lam, C. A. Van Hasselt |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Histamine H1 Antagonists Non-Sedating medicine.medical_specialty Allergy Rhinitis Allergic Perennial Severity of Illness Index Quality of life Internal medicine Immunopathology Severity of illness medicine Humans Prospective Studies Prospective cohort study Desloratadine business.industry Endoscopy General Medicine Loratadine Middle Aged medicine.disease Symptomatic relief Surgery Clinical trial Treatment Outcome Otorhinolaryngology Chronic Disease Quality of Life Female business medicine.drug |
| Zdroj: | The Journal of Laryngology & Otology. 121:1151-1155 |
| ISSN: | 1748-5460 0022-2151 |
| Popis: | Objective:To evaluate the outcome and the change in quality of life of patients with chronic rhinitis after treatment with desloratadine.Study design:A prospective, open-label, non-blinded, non-randomised study of patients in a secondary and tertiary ENT referral centre.Methods:Chinese patients with chronic rhinitis were recruited. The patients were assessed by a questionnaire that included rhinitis symptoms score and SF-36 health survey components. Endoscopic assessment was performed with a rigid nasoendoscope and scored according to the modified endoscopic appearance score of Lund and Kennedy. A 12-week course of desloratadine 5 mg daily was prescribed. Patients were re-evaluated after treatment. A total of 47 subjects completed the study.Results:There were significant reductions in median rhinitis symptoms score, from six to five (p p p == 0.022).Conclusion:Desloratadine may be an effective treatment which provides symptomatic relief and improves the quality of life in patients with chronic rhinitis. |
| Databáze: | OpenAIRE |
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