Ultrastructural immunocytochemistry of autoimmune bullous diseases
| Autor: | Anthony J. Karpouzis, Nicholas Stavrianeas, Elma Koumantaki-Mathioudaki, Myrsini Karpouzi, Emmanuel Vamvassakis, Anthony Vareltzides |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Epidermolysis bullosa acquisita
Adult Male Pemphigoid Pathology medicine.medical_specialty Immunoelectron microscopy Dermatology Autoimmune Diseases Dermatitis herpetiformis Immunopathology medicine Humans Cicatricial pemphigoid skin and connective tissue diseases Microscopy Immunoelectron Aged Autoantibodies Skin Autoimmune disease Aged 80 and over integumentary system Skin Diseases Vesiculobullous business.industry Middle Aged medicine.disease eye diseases Pemphigus Female business |
| Zdroj: | The Australasian journal of dermatology. 43(2) |
| ISSN: | 0004-8380 |
| Popis: | Advanced immunopathological assays have been developed to elucidate the pathophysiology and provide more precise nosological definitions of the immunobullous diseases. Forty-seven patients suffering from autoimmune bullous diseases (intra- or subepidermal) were studied by immunoelectron microscopy (direct and indirect). Peroxidase staining was revealed by diaminobenzidine (determination of immune deposit location) in the majority of the cases of subepidermal bullous diseases, but in less than half of the cases of intraepidermal bullous diseases. Immunoelectron microscopy features contributed in verifying the diagnosis of rare entities such as cicatricial pemphigoid, paraneoplastic autoimmune bullous disease, linear IgA disease and epidermolysis bullosa acquisita. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|