Percutaneous closure of perimembranous ventricular septal defect using patent ductus arteriosus occluders

Autor: Hoyoun Won, Hieu Lan Nguyen, Seung Yong Shin, Quang Tan Phan, Hieu Ba Tran, Julian Johny Thottian, Linh Huynh Dinh, Saima Sharmin, Dung Duc Doan, Truong Q. Nguyen, Sang Wook Kim, Wang Soo Lee
Rok vydání: 2018
Předmět:
Heart Septal Defects
Ventricular
Male
Percutaneous
Septal Occluder Device
Perimembranous ventricular septal defect
lcsh:Medicine
Blood Pressure
030204 cardiovascular system & hematology
Vascular Medicine
Diagnostic Radiology
Electrocardiography
0302 clinical medicine
Postoperative Complications
Ductus arteriosus
Ultrasound Imaging
Medicine and Health Sciences
Morphogenesis
030212 general & internal medicine
lcsh:Science
Child
Heart septal defect
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
Heart
Congenital Heart Defects
Systolic Pressure
medicine.anatomical_structure
Treatment Outcome
Echocardiography
Child
Preschool
Aortic Valve
Engineering and Technology
Female
Patient Safety
Anatomy
Research Article
Biotechnology
medicine.medical_specialty
Adolescent
Heart block
Imaging Techniques
Cardiac Ventricles
Cardiology
Bioengineering
Surgical and Invasive Medical Procedures
Prosthesis Design
Research and Analysis Methods
03 medical and health sciences
Diagnostic Medicine
medicine
Congenital Disorders
Humans
Birth Defects
business.industry
lcsh:R
Biology and Life Sciences
medicine.disease
Surgery
Blood pressure
Ventricular Septal Defects
Cardiovascular Anatomy
lcsh:Q
Medical Devices and Equipment
business
Follow-Up Studies
Developmental Biology
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206535 (2018)
ISSN: 1932-6203
Popis: Objectives To assess the safety and efficacy of percutaneous closure of perimembranous ventricular septal defect (PmVSD) using patent ductus arteriosus (PDA) occluders. Background Widespread use of conventional PmVSD closure devices has been limited by unacceptable high rate of complete heart block (CHB). The elegant design of PDA occluders is supposed to ease implantation, increase closure rate and minimize damage to adjacent structures. Thus, PDA occluders may reduce complications, especially the CHB, and offer a good alternative for PmVSD closure. Method From September 2008 to October 2015, patients who underwent attempted percutaneous VSD closure using PDA occluders were included in the study. Patient demographics, echocardiography measurements, procedure details and follow-up data until October 2017 were collected. Results In total, 321 patients with a mean age of 15.5±12.6 years and mean a weight of 33.3±20.5 kg were included in this study. The mean defect size was 4.8±2.1 mm. Implantation was successful in 307 (95.6%) patients. The median follow-up time was 63 months (24 to 108 months). The closure rates were 89.5%, 91.5%, and 99.3% after the procedure 24 hours, 6 months and 2 years, respectively. Major complications occurred in 5 (1.7%) patients during the procedure and follow-up, including persistent CHB in 2 (0.7%) patients and device embolization in 3 (1.0%) patients. No death, disability, or other major complication was detected. Conclusion Percutaneous closure of PmVSD using PDA occluders is feasible, safe and efficacious in selected patients.
Databáze: OpenAIRE
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