Bilirubin Production in Endotoxin-Treated or Tumor-Bearing Rats
| Autor: | Carl L. Eddington, Ralph F. Kampschmidt |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
medicine.medical_specialty
Time Factors Chemistry Bilirubin Iron Walker carcinoma 256 General Biochemistry Genetics and Molecular Biology Rats Endotoxins chemistry.chemical_compound Endocrinology Conjugate bilirubin Internal medicine Concomitant Escherichia coli medicine Animals Female Carcinoma 256 Walker Heme Injections Intraperitoneal |
| Zdroj: | Experimental Biology and Medicine. 129:580-584 |
| ISSN: | 1535-3699 1535-3702 |
| Popis: | SummaryBilirubin production was found to increase twofold during the first 24 hr after administering 100 μg endotoxin (intraperitoneally) to rats. A 50% increase in bilirubin production was observed in host rats 7 days after transplant of the Walker carcinoma 256 (intramuscularly). Ability of the liver to conjugate bilirubin was normal in both types of animals. The results obtained are consistent with the view that the concomitant block in re-utilization of iron occurs at some point after its release from heme. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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