Successful treatment of a cervical pregnancy with a single low dose methotrexate regimen
| Autor: | M. Cathleen McCoy, Jeffrey A. Kuller, Vern L. Katz, Deborah J. Dotters |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Gestational sac Cervical pregnancy Cervix Uteri Chorionic Gonadotropin Pregnancy medicine Humans Vaginal bleeding Ultrasonography Hysterectomy Ectopic pregnancy Obstetrics business.industry Fetal pole Obstetrics and Gynecology Middle Aged medicine.disease Pregnancy Ectopic Surgery Methotrexate medicine.anatomical_structure Reproductive Medicine Gestation Female Uterine Hemorrhage medicine.symptom business medicine.drug |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 60:187-189 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/0028-2243(95)02039-u |
| Popis: | Until very recently cervical pregnancies have been treated with surgery, usually hysterectomy. The development of endovaginal ultrasound, which allows early diagnosis, and methotrexate chemotherapy have opened up new therapeutic options. A 45-year-old multigravida presented at 8 weeks' gestation with vaginal bleeding. Endovaginal ultrasound demonstrated a cervical pregnancy with a fetal pole, 1.2 × 1.4 cm sac, no cardiac pulsations, and an empty uterus. After discussion with the patient, single low dose methotrexate 1.5 mg/m 2 was given intramuscularly. The patient's hCG titre was 5882 IU-(Third International Standard). Over a 5-week period the hCG titres fell, and the gestational sac disappeared. The patient experienced intermittent vaginal bleeding and cramping but was managed as an outpatient. Single low dose methotrexate may be a successful management option in selected cases of cervical pregnancy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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