Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide]
| Autor: | Richard I. Cooper, Chu-Yi Yu, Renate van Well, Xiang-Guo Hu, George W. J. Fleet, Francis Xavier Wilson, Robert J. Nash, David J. Watkin, Agnieszka Michalik, Amber L. Thompson, Peter David Johnson |
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| Rok vydání: | 2009 |
| Předmět: |
Chemical crystallography
Crystallography Stereochemistry Hydrogen bond Alkaloid Diol Organic chemistry Indolizidine General Chemistry Crystal structure Condensed Matter Physics Organic Papers chemistry.chemical_compound Stevia rebaudiana chemistry QD901-999 Bromide General Materials Science Indolizine |
| Zdroj: | Acta Crystallographica Section E: Structure Reports Acta Crystallographica Section E, Vol 65, Iss 11, Pp o2904-o2905 (2009) |
| ISSN: | 1600-5368 |
| Popis: | X-ray crystallographic analysis of the title hydrobromide salt, C10H20N+·Br−, of (1R,2S,3R,5R,8aR)-3-hydroxymethyl-5-methyloctahydroindolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxylated indolizidine alkaloid isolated from Stevia rebaudiana (Asteraceae) leaves. In the crystal structure, molecules are linked by intermolecular O—H...Br and N—H...Br hydrogen bonds, forming double chains around the twofold screw axes along the b-axis direction. Intramolecular O—H...O interactions occur. |
| Databáze: | OpenAIRE |
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