Anemia and mortality in hemodialysis patients: Accounting for morbidity and treatment variables updated over time
| Autor: | Marshall M. Joffe, Ronald L. Pisoni, F. K. Port, Jeffrey S. Berns, Harold I. Feldman, Bruce M. Robinson |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Anemia medicine.medical_treatment 030232 urology & nephrology Accounting 030204 cardiovascular system & hematology Hemoglobins 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Renal Dialysis Epidemiology medicine Humans Dialysis Survival analysis hemodialysis business.industry Confounding hemoglobin Middle Aged medicine.disease Survival Analysis 3. Good health Nephrology Multivariate Analysis Kidney Failure Chronic Female Observational study Hemodialysis Morbidity business Follow-Up Studies Cohort study |
| Zdroj: | Kidney International. 68:2323-2330 |
| ISSN: | 0085-2538 |
| Popis: | Anemia and mortality in hemodialysis patients: Accounting for morbidity and treatment variables updated over time.BackgroundThe objective of this study was to gain insight into the associations of anemia with mortality among maintenance hemodialysis (HD) patients and patient subgroups by an analysis that more comprehensively represents hemoglobin (Hb) level, morbidity, and treatment characteristics over time than was possible in prior observational studies.MethodsA cohort study was conducted among 5517 subjects in the American arm of the Dialysis Outcomes and Practice Patterns Study Phase I. We used proportional hazard analysis to model all-cause mortality as a function of Hb level measured 1, 3, and 6 months previously. Forty-five potentially confounding patient-level characteristics were considered, including demographics, comorbidities, and time-updated levels of erythropoietin and parenteral iron dosing, medical events, and laboratory and dialysis measures.ResultsCompared to Hb 11 to |
| Databáze: | OpenAIRE |
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