Risks and outcomes associated with primary intraocular lens implantation in children under 2 years of age: the IoLunder2 cohort study

Autor: Phillippa M. Cumberland, Ameenat Lola Solebo, Isabelle Russell-Eggitt, Jugnoo S Rahi
Rok vydání: 2015
Předmět:
Zdroj: British Journal of Ophthalmology. 99:1471-1476
ISSN: 1468-2079
0007-1161
Popis: Background/aims To investigate outcomes following cataract surgery with and without primary intraocular lens (IoL) implantation in children under 2 years of age with congenital or infantile cataract. Method Prospective population based cohort study undertaken through the British Isles Congenital Cataract Interest Group, with systematic data collection on children undergoing surgery in UK and Ireland between January 2009 and December 2010. ORs for the association between IoL implantation and visual acuity, postoperative glaucoma and reoperation at 1 year after surgery were estimated using multivariable regression analysis to control for potential confounders. Results Of 221 children, 56/131 with bilateral and 48/ 90 with unilateral cataract underwent primary IoL implantation. IoL implantation was independently associated with better visual outcome in bilateral (OR 4.6, 95% CI 1.6 to 13.1, p=0.004) but not unilateral disease. IoL use increased the odds of reoperation requiring repeat general anaesthetic (bilateral OR 5.5, p
Databáze: OpenAIRE