Correlating Cochlear Morphometrics from Parnell’s Mustached Bat (Pteronotus parnellii) with Hearing
| Autor: | Maria Morell, Jodie Ng, Robert E. Shadwick, Cassandra D. Girdlestone, Adrien Caplot, Manfred Kössl |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Biometry 01 natural sciences Pteronotus parnellii 03 medical and health sciences 0302 clinical medicine Hearing Chiroptera 0103 physical sciences otorhinolaryngologic diseases medicine Animals Inner ear 010301 acoustics Cochlea Audio frequency Morphometrics biology Anatomy biology.organism_classification Sensory Systems Rats medicine.anatomical_structure Otorhinolaryngology Organ of Corti Female sense organs Hair cell Transduction (physiology) 030217 neurology & neurosurgery Research Article |
| Zdroj: | J Assoc Res Otolaryngol |
| ISSN: | 1438-7573 1525-3961 |
| DOI: | 10.1007/s10162-020-00764-1 |
| Popis: | Morphometric analysis of the inner ear of mammals can provide information for cochlear frequency mapping, a species-specific designation of locations in the cochlea at which different sound frequencies are encoded. Morphometric variation occurs in the hair cells of the organ of Corti along the cochlea, with the base encoding the highest frequency sounds and the apex encoding the lowest frequencies. Changes in cell shape and spacing can yield additional information about the biophysical basis of cochlear tuning mechanisms. Here, we investigate how morphometric analysis of hair cells in mammals can be used to predict the relationship between frequency and cochlear location. We used linear and geometric morphometrics to analyze scanning electron micrographs of the hair cells of the cochleae in Parnell’s mustached bat (Pteronotus parnellii) and Wistar rat (Rattus norvegicus) and determined a relationship between cochlear morphometrics and their frequency map. Sixteen of twenty-two of the morphometric parameters analyzed showed a significant change along the cochlea, including the distance between the rows of hair cells, outer hair cell width, and gap width between hair cells. A multiple linear regression model revealed that nine of these parameters are responsible for 86.9 % of the variation in these morphometric data. Determining the most biologically relevant measurements related to frequency detection can give us a greater understanding of the essential biomechanical characteristics for frequency selectivity during sound transduction in a diversity of animals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10162-020-00764-1) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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