Engineering microbial chemical factories to produce renewable 'biomonomers'
| Autor: | Shawn Pugh, Rebekah McKenna, David R. Nielsen, Jake Adkins |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
business.industry lcsh:QR1-502 Plastic materials biopolymers Review Article monomer Biology sustainability monomers Microbiology Bioplastic lcsh:Microbiology Biotechnology Renewable energy Metabolic engineering bioplastics Synthetic Biology Biochemical engineering metabolic engineering business bioplastic Speciality chemicals |
| Zdroj: | Frontiers in Microbiology Frontiers in Microbiology, Vol 3 (2012) |
| ISSN: | 1664-302X |
| DOI: | 10.3389/fmicb.2012.00313 |
| Popis: | By applying metabolic engineering tools and strategies to engineer synthetic enzyme pathways, the number and diversity of commodity and specialty chemicals that can be derived directly from renewable feedstocks is rapidly and continually expanding. This of course includes a number of monomer building-block chemicals that can be used to produce replacements to many conventional plastic materials. This review aims to highlight numerous recent and important advancements in the microbial production of these so-called ‘biomonomers’. Relative to naturally-occurring renewable bioplastics, biomonomers offer several important advantages, including improved control over the final polymer structure and purity, the ability to synthesize non-natural copolymers, and allowing products to be excreted from cells which ultimately streamlines downstream recovery and purification. To highlight these features, a handful of biomonomers have been selected as illustrative examples of recent works, including polyamide monomers, styrenic vinyls, hydroxyacids, and diols. Where appropriate, examples of their industrial penetration to date and end-product uses are also highlighted. Novel biomonomers such as these are ultimately paving the way towards new classes of renewable bioplastics that possess a broader diversity of properties than ever before possible. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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