Blood conservation effect and safety of shed mediastinal blood autotransfusion after cardiac surgery
| Autor: | Osamu Date, Kouji Ban, Tomohiro Nakamura, Tatsuhiko Komiya, Kazuhiro Yamazaki, Yoshio Kanzaki |
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| Rok vydání: | 1998 |
| Předmět: |
Male
medicine.medical_specialty Blood conservation business.industry Mediastinum Middle Aged Surgery Cardiac surgery Blood Transfusion Autologous Homologous blood Cardiothoracic surgery Hemostasis Anesthesia Drainage Humans Medicine Female Cardiac Surgical Procedures Safety Cardiology and Cardiovascular Medicine business Tranexamic acid Fibrinogen degradation product Autotransfusion medicine.drug |
| Zdroj: | The Japanese Journal of Thoracic and Cardiovascular Surgery. 46:961-965 |
| ISSN: | 1863-2092 1344-4964 |
| DOI: | 10.1007/bf03217855 |
| Popis: | Autotransfusion of shed mediastinal blood after cardiac surgery has been used to reduce risks related to homologous blood transfusions. To document the efficacy and safety of autotransfusion, we compared clinical findings of 80 patients receiving shed mediastinal blood (autotransfusion group) with those of the control group of 52 patients. The amount of the autotransfusion was limited to 800 ml, given the potentially harmful effects of shed blood transfusion. The mean transfused shed volume was 314 +/- 236 ml (S.D.). The serum levels of FDP-E, D-dimer and TAT after autotransfusion were higher in the autotransfusion group than in the control group (p = 0.01, p = 0.0004, p = 0.001, respectively). However, postoperative blood loss and the rate of reexploration for bleeding were similar in the two groups. The patients receiving blood products were fewer in the autotransfusion group than those in the control group (21% vs 44%; p = 0.005). Autotransfusion did not increase postoperative complications, including infection. Thus, although autotransfusion of mediastinal shed blood has the potential to affect hemostasis, unless the amount of autotransfusion exceeds 800 ml, it appears that this method is clinically safe and effective as a mean of blood conservation. |
| Databáze: | OpenAIRE |
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