Peripheral and periosteal chondrosarcoma: MRI-pathological correlation in 58 cases
| Autor: | Asif Saifuddin, William Tilden, Paul O'Donnell, Vanghelita Andrei |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Chondrosarcoma Bone Neoplasms Bone and Bones Resection Young Adult Periosteal chondrosarcoma Medicine Humans Radiology Nuclear Medicine and imaging Atypical cartilaginous tumour Child Pathological correlation Aged Retrospective Studies Aged 80 and over Hyperplasia business.industry Histology Middle Aged Magnetic Resonance Imaging Spine Peripheral Orthopedic surgery Female Radiology business Bone surface |
| Zdroj: | Skeletal radiology. 51(6) |
| ISSN: | 1432-2161 |
| Popis: | OBJECTIVE To determine whether MRI can distinguish atypical cartilaginous tumour/grade 1 peripheral/periosteal chondrosarcoma (ACT/Gd1 PP-CS) from high-grade peripheral/periosteal chondrosarcoma (HG-PP-CS) or dedifferentiated peripheral/periosteal chondrosarcoma (DD-PP-CS). MATERIALS AND METHODS Retrospective review of patients diagnosed between January 2007 and December 2020 who had undergone resection of PP-CS. Data collected included age, sex, and skeletal location. Histological tumour grades based on surgical resection were classified as ACT/grade 1 PP-CS, HG-PP-CS, or DD-PP-CS. A variety of MRI features were reviewed independently by 2 musculoskeletal radiologists blinded to final diagnosis and compared between the 3 groups. For statistical analysis, HG-PP-CS and DD-PP-CS were combined. RESULTS Fifty-eight patients fulfilled the inclusion criteria, 31 (53%) males and 27 (47%) females with a mean age at diagnosis of 46.1 years (range 11-83 years), 14 (24%) of whom had an underlying diagnosis of diaphyseal aclasis. Forty-one (70.7%) cases were peripheral and 17 (29.3%) periosteal, 38 (66%) involving the flat bones, 15 (26%) the major long bones, 3 (5%) the spine, and 2 (3%) the bones of the hands and feet. Final histology revealed 33 (57%) ACT/Gd1-PP-CS, 18 (31%) HG-PP-CS, and 7 (12%) DD-PP-CS. Periosteal tumours were 16 times more likely to be HG/DD-CS compared to peripheral tumours (p |
| Databáze: | OpenAIRE |
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