| Autor: |
Rose Q, Trieu, Yoav, Mazor, Gillian, Prott, Michael P, Jones, John E, Kellow, Margaret, Schnitzler, Allison, Malcolm |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Diseases of the Colon & Rectum. 66:591-597 |
| ISSN: |
0012-3706 |
| DOI: |
10.1097/dcr.0000000000002422 |
| Popis: |
Incontinence to gas can be a troublesome symptom impacting on patients' quality of life even in the absence of fecal incontinence. Whether isolated flatus incontinence represents part of the spectrum of true fecal incontinence or a separate condition with a different pathophysiology remains unclear.To evaluate the clinical features and anorectal physiology in women presenting with severe isolated flatus incontinence, compared to fecal incontinence and healthy asymptomatic women.This was a retrospective case-control study of prospectively collected data.Data from participants was obtained from a single tertiary Neurogastroenterology Unit in Sydney, Australia.Data from 34 patients with severe isolated flatus incontinence, alongside 127 women with fecal incontinence and 44 healthy women was analyzed.The primary outcomes were clinical (including demographics, obstetrics and symptom variables), as well as physiological differences across the three groups.Flatus incontinence patients were significantly younger (mean 39 year versus 63 year, p = 0.0001), had a shorter history of experiencing their symptom (p = 0.0001) and had harder stool form than fecal incontinence patients (p = 0.02). Those with flatus incontinence had an adverse obstetric history and impaired anorectal physiology (motor and sensory, specifically rectal hypersensitivity); although to a lesser extent than patients with fecal incontinence.This study was limited by its retrospective design and modest sample size.Anorectal physiology was impaired in flatus incontinence patients compared to healthy controls, but to a lesser extent than in those with fecal incontinence, raising the possibility that flatus incontinence could be a precursor to fecal incontinence. As clinical and physiological findings are different to healthy controls (including the presence of visceral hypersensitivity), isolated flatus incontinence should be considered as a distinct clinical entity (like other functional gastrointestinal disorders), or possibly part of an incontinence spectrum rather than purely a normal phenomenon. See Video Abstract at http://links.lww.com/DCR/B946. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
