Manufacturing and wetting low-cost microfluidic cell separation devices

Autor: Ryan S. Pawell, David W. Inglis, Robert A. Taylor, Tracie Barber
Rok vydání: 2013
Předmět:
Zdroj: Biomicrofluidics. 7(5)
ISSN: 1932-1058
Popis: Deterministic lateral displacement (DLD) is a microfluidic size-based particle separation or filter technology with applications in cell separation and enrichment. Currently, there are no cost-effective manufacturing methods for this promising microfluidic technology. In this fabrication paper, however, we develop a simple, yet robust protocol for thermoplastic DLD devices using regulatory-approved materials and biocompatible methods. The final standalone device allowed for volumetric flow rates of 660 μl min−1 while reducing the manufacturing time to
Databáze: OpenAIRE