Differences and determinants of vitamin D deficiency among UK biobank participants: a cross-ethnic and socioeconomic study
| Autor: | Ang Zhou, Joshua Sutherland, Elina Hyppönen, Matthew J Leach |
|---|---|
| Přispěvatelé: | Sutherland, Joshua P, Zhou, Ang, Leach, Matthew J, Hypponen, Elina |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Databases Factual Black african vitamin D deficiency Ethnic group Nutritional Status 030209 endocrinology & metabolism vitamin D socioeconomic factors Critical Care and Intensive Care Medicine Logistic regression ethnic groups 03 medical and health sciences 0302 clinical medicine Prevalence medicine Vitamin D and neurology Humans Socioeconomic status 030109 nutrition & dietetics Nutrition and Dietetics business.industry Public health public health Middle Aged Vitamin D Deficiency medicine.disease Biobank United Kingdom Diet nutritional status Socioeconomic Factors Female business Demography |
| Popis: | Background: The public health relevance of true vitamin D deficiency is undisputed, although controversy remains regarding optimal vitamin D status. Few contemporary cross-ethnic studies have investigated the prevalence and determinants of very low 25-hydroxyvitamin D [25(OH)D] concentrations. Methods: We conducted cross-ethnic analyses on the prevalence and determinants of vitamin D deficiency (25(OH)D ≤ 25 nmol/L) using data from 440,581 UK Biobank participants, of which 415,903 identified as White European, 7880 Asian, 7602 Black African, 1383 Chinese, and 6473 of mixed ancestry. Determinants of vitamin D deficiency were examined by logistic regression. Results: The prevalence of vitamin D deficiency was highest among participants of Asian ancestry (57.2% in winter/spring and 50.8% in summer/autumn) followed by those of Black African ancestry (38.5% and 30.8%, respectively), mixed (36.5%, 22.5%), Chinese (33.1%, 20.7%) and White European ancestry (17.5%, 5.9%). Participants with higher socioeconomic deprivation were more likely to have 25(OH)D deficiency compared to less deprived participants (P = |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|