Sjögren’s syndrome and lymphadenopathy unraveling the diagnosis of Lyme disease
| Autor: | Svitlana Smiyan, Igor Galaychuk, Sofiya Gusak, Volodymyr Nykolyuk, Ivan Bilozetsky, Igor V. Zhulkevych, Roman Komorovsky |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Immunology lcsh:Medicine Case Report Disease 03 medical and health sciences 0302 clinical medicine Lyme disease Rheumatology lymphadenopathy Immunology and Allergy Medicine Borrelia burgdorferi Lymph node 030203 arthritis & rheumatology biology business.industry lcsh:R Borrelia Burgdorferi Infection medicine.disease biology.organism_classification bacterial infections and mycoses Dermatology Lymphoma medicine.anatomical_structure Sjögren’s syndrome Immunohistochemistry business Generalized lymphadenopathy |
| Zdroj: | Reumatologia Rheumatology, Vol 57, Iss 1, Pp 59-62 (2019) |
| ISSN: | 2084-9834 0034-6233 |
| Popis: | Lyme disease is a multisystem tick-borne transmissive disease with heterogeneous manifestations, frequently making the diagnosis difficult in clinical practice. Herein, we report a case of a 43-year-old female patient who presented with generalized lymphadenopathy requiring a further diagnostic evaluation towards lymphoma. The patient also had clinical signs of Sjögren’s syndrome. Lymph node excision with subsequent histological and immunohistochemical studies were performed. While light microscopy findings were suspicious for lymphoma, immunohistochemistry results were consistent with cortical and paracortical lymph node hyperplasia with no evidence of lymphoproliferative disorder. Further laboratory testing confirmed the presence of Lyme borreliosis. Effectiveness of the administered antibiotic therapy confirmed Borrelia burgdorferi infection. Interrelationships between Sjögren’s syndrome, lymphadenopathy and Lyme disease are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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