Establishment of reference serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels of Tunisian children during childhood and adolescence
Autor: | Zouhair Tabka, Abdelkrim Zbidi, S. Sfar, S. Ben Mdalla, H. Knani, A. Baklouti, M. Zaouali Ajina |
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Rok vydání: | 2009 |
Předmět: |
Male
medicine.medical_specialty Tunisia Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment Serum insulin Population Insulin-like growth factor-binding protein Endocrinology Sex Factors Reference Values Internal medicine Medicine Humans Insulin-Like Growth Factor I education Child Puberty stage education.field_of_study biology business.industry Growth factor Puberty Age Factors Insulin-Like Growth Factor Binding Protein 3 biology.protein Female business |
Zdroj: | Journal of endocrinological investigation. 32(8) |
ISSN: | 1720-8386 |
Popis: | Background: The aim of the present study is to establish age- and sex-related reference ranges of serum IGF-I and IGF binding protein-3 (IGFBP-3) levels in a pattern of Tunisian children. Subjects and methods: Two hundred healthy Tunisian children (103 boys and 97 girls), aged between 6 and 16 yr, were considered in the study. Results: Mean serum levels of IGF-I and IGFBP-3 are observed to be higher in girls compared to boys of the same age interval. However, these differences were statistically significant only in pubertal ages (11–14 yr) for IGF-I and in pre-pubertal ages (6–10 yr) for IGFBP-3 (p |
Databáze: | OpenAIRE |
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