CD99 immunoreactivity in follicular dendritic cell tumour: original observation prompted by an unusual cervical spine lesion
| Autor: | S J Nayler, A Y Kalebi, M J Hale |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty CD99 Dendritic Cell Sarcoma Follicular HIV Infections Biology 12E7 Antigen Pathology and Forensic Medicine Lesion Antigens CD medicine Humans Pathological Lymph node Spinal Neoplasms CD23 Intervertebral disc General Medicine Anatomy medicine.disease Magnetic Resonance Imaging Neoplasm Proteins medicine.anatomical_structure Sarcoma medicine.symptom Follicular dendritic cell tumour Cell Adhesion Molecules |
| Zdroj: | Journal of clinical pathology. 61(7) |
| ISSN: | 1472-4146 |
| Popis: | Follicular dendritic cell tumour/sarcoma (FDCT) is a rare tumour that characteristically shows immunoreactivity for CD21, CD23 and CD35.1 To date there is no published literature on CD99 immunoreactivity in FDCT. We recently encountered two cases of FDCT, both of which expressed CD99. The first patient (case 1) was a HIV-positive man in his 30s who had an extensive extradural spinal mass (fig 1A) which infiltrated the C4/C5 intervertebral disc causing pathological fracture of C5 with posterior subluxation (fig 1B, C). The patient had been diagnosed 2 years previously with FDCT in a cervical lymph node that was completely excised. Histological examination of the spinal lesion revealed a spindle cell tumour arranged in interlacing fascicles, with some areas of whorling, and scattered infiltrate of small lymphocytes. The spindle cells … |
| Databáze: | OpenAIRE |
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