Inter-method reliability of the modified Rankin Scale in patients with subarachnoid hemorrhage

Autor: Wim I. M. Verhagen, Inger L. Abma, P.J. van der Wees, R Haeren, H Schenck, Hieronymus D. Boogaarts, Edith Nobels-Janssen, E N Postma, M H den Hertog, Bert A Coert, D Nanda, Dagmar Verbaan, Ronald H. M. A. Bartels, Adriaan R E Potgieser, W A Moojen, J M C van Dijk
Přispěvatelé: RS: MHeNs - R3 - Neuroscience, MUMC+: MA Med Staf Spec Neurochirurgie (9), Neurochirurgie, Movement Disorder (MD), Graduate School, Neurosurgery, ANS - Neurovascular Disorders
Rok vydání: 2022
Předmět:
medicine.medical_specialty
TELEPHONE
Subarachnoid hemorrhage
Modified Rankin Scale
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]
Outcome Assessment
Health Care
Humans
Medicine
Prospective Studies
Stroke
Reliability (statistics)
Neuroradiology
OUTCOMES
Original Communication
business.industry
Other Research Radboud Institute for Health Sciences [Radboudumc 0]
Reproducibility of Results
medicine.disease
Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]
Reliability
Clinical trial
Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]
Treatment Outcome
Neurology
nervous system
AGREEMENT
Structured interview
Physical therapy
Neurology (clinical)
business
Kappa
STROKE
Zdroj: Journal of Neurology, 269, 5, pp. 2734-2742
Journal of Neurology, 269(5), 2734-2742. Springer
Journal of Neurology, 269, 2734-2742. SPRINGER HEIDELBERG
Journal of Neurology, 269. SPRINGER HEIDELBERG
Journal of Neurology, 269, 2734-2742
Journal of Neurology
Journal of neurology. D. Steinkopff-Verlag
ISSN: 0340-5354
Popis: Background and objectives The modified Rankin Scale (mRS) is one of the most frequently used outcome measures in trials in patients with an aneurysmal subarachnoid hemorrhage (aSAH). The assessment method of the mRS is often not clearly described in trials, while the method used might influence the mRS score. The aim of this study is to evaluate the inter-method reliability of different assessment methods of the mRS. Methods This is a prospective, randomized, multicenter study with follow-up at 6 weeks and 6 months. Patients aged ≥ 18 years with aSAH were randomized to either a structured interview or a self-assessment of the mRS. Patients were seen by a physician who assigned an mRS score, followed by either the structured interview or the self-assessment. Inter-method reliability was assessed with the quadratic weighted kappa score and percentage of agreement. Assessment of feasibility of the self-assessment was done by a feasibility questionnaire. Results The quadratic weighted kappa was 0.60 between the assessment of the physician and structured interview and 0.56 between assessment of the physician and self-assessment. Percentage agreement was, respectively, 50.8 and 19.6%. The assessment of the mRS through a structured interview and by self-assessment resulted in systematically higher mRS scores than the mRS scored by the physician. Self-assessment of the mRS was proven feasible. Discussion The mRS scores obtained with different assessment methods differ significantly. The agreement between the scores is low, although the reliability between the assessment methods is good. This should be considered when using the mRS in clinical trials. Trial registration www.trialregister.nl; Unique identifier: NL7859.
Databáze: OpenAIRE
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