Development and Validation of a Biobank Questionnaire Intended for the Public in the Arab Region
| Autor: | Manal Shahouri, Nada Taha Mostafa, Alya Isam Elgamri, Fatma Abdelgawad, Karima El Rhazi, Latifa Adarmouch, Ehsan B. Gamel, Ahmed Samir Abdelhafiz, Samar Abd ElHafeez, Mamoun Ahram, Henry Silverman, Maha Emad Ibrahim, Zeinab Mohammed, Eman H Elsebaie |
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| Rok vydání: | 2021 |
| Předmět: |
validity
reliability questionnaire public Medicine (miscellaneous) Reproducibility of Results Cell Biology General Medicine Original Articles psychometric properties Biobank General Biochemistry Genetics and Molecular Biology Arabs Cross-Sectional Studies biobanking Donation Political science Surveys and Questionnaires Humans Engineering ethics Reliability (statistics) Biological Specimen Banks |
| Zdroj: | Biopreservation and Biobanking |
| ISSN: | 1947-5543 |
| Popis: | Background: Assessing the public perspectives regarding donation of biospecimens to biobanks would be helpful with the establishment of biobanks in the Arab region. Objective: To develop a biobanking questionnaire in Arabic and assess its psychometric properties. Design: Multicenter cross-sectional study. Methods: We used a two-step process for questionnaire development. First, we decided on the important constructs for a questionnaire followed by development of an item pool through review of the scientific literature and published questionnaires. The questionnaire was refined through cognitive interviews and translation. An expert panel assessed content validity. The final questionnaire included five domains: perceptions; aspects important to participation in biobank research; preferences for type of biobank; attitudes toward biobanking; and willingness to participate in biobank research. Second, we distributed the questionnaire to 250 members of the public from Egypt, Jordan, Sudan, and Morocco to assess the questionnaire's psychometric properties, including reliability (internal consistency and Cronbach's alpha) and construct validity (convergent and divergent validity and exploratory factor analysis [EFA]). Results: Internal consistency yielded a range of Cronbach's alpha for the five domains from 0.62 to 0.80. EFA showed a 12-factorial solution. Kaiser-Meyer-Olkin measure of sampling adequacy was 0.907 and Bartlett's test of sphericity was significant (p |
| Databáze: | OpenAIRE |
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