| Autor: |
Michelle J. Gould, Jenna Dowhaniuk, Jorge Arredondo, Paul Azzopardi, Tina Hu, Heather Mileski, Andrea Carpenter, Nikhil Pai, Herbert Brill |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of pediatric gastroenterology and nutrition. |
| ISSN: |
1536-4801 |
| Popis: |
The incidence of celiac disease in first-degree relatives of affected individuals is higher than in the general population, yet the clinical characteristics of this unique subset of patients has not been well described. Through a retrospective review of patients seen in a tertiary care pediatric celiac disease clinic, we identified 49 patients diagnosed with celiac disease following screening due to an affected first-degree relative. Although 51% of patients screened due to an affected first-degree relative were asymptomatic, their disease histology was as severe as those screened for symptoms suggestive of celiac disease. These findings support current recommendations to screen all first-degree relatives of patients with celiac disease regardless of clinical symptoms. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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