Squamous cell carcinoma with sarcoma-like stroma of the female genital tract. Clinicopathologic study of four cases
| Autor: | Francesco Piscioli, Juan Rosai, Theresa A. Steeper |
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| Rok vydání: | 1983 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty Vaginal Neoplasms Genital Neoplasms Female Cell Uterine Cervical Neoplasms Fibroma Vulva Diagnosis Differential Stroma Carcinosarcoma medicine Humans Respiratory system Cervix Aged Vulvar Neoplasms business.industry Histocytochemistry Sarcoma Middle Aged medicine.disease medicine.anatomical_structure Oncology Vagina Carcinoma Squamous Cell Immunohistochemistry Keratins Female business Follow-Up Studies |
| Zdroj: | Cancer. 52(5) |
| ISSN: | 0008-543X |
| Popis: | Four cases of squamous cell carcinoma with sarcoma-like stroma located in the vulva (1), vagina (2) and cervix (1) of postmenopausal women are presented. The gross and microscopic features are very similar to those of similarly named tumors occurring in the upper respiratory and digestive tract and in the skin. Light microscopic, electron microscopic, and immunohistochemical examination provided convincing evidence that these tumors are composed solely of squamous cell carcinoma, which has undergone a spindle cell sarcoma-like transformation in the deeper portions. Follow-up revealed an aggressive clinical course in three of the four patients, who died of their tumor between 2 and 45 months after presentation. At the time of death, two of the patients had widespread metastases and the other had massive local recurrence. |
| Databáze: | OpenAIRE |
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