Postmortem Tryptase Level in 120 Consecutive Nonanaphylactic Deaths
| Autor: | Suneeth Mathew, Jack Garland, Rexson Tse, Leo Lam, Sinead McCarthy, Simon Stables, Yeri Ahn, Lina Woydt, Sarah Hensby-Bennett, Paul Morrow, Benjamin Ondrushka, Ugo Da Broi, Charley Glenn, Cristian Palmiere, Winston Philcox, Kilak Kesha, Kelly Olds |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Percentile medicine.medical_specialty Resuscitation Adolescent Reference range Tryptase Gastroenterology Postmortem Changes Pathology and Forensic Medicine Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Reference Values Cause of Death Internal medicine medicine Humans 030216 legal & forensic medicine Aged Cause of death Aged 80 and over biology business.industry Middle Aged medicine.disease Reference values biology.protein Female Tryptases business Anaphylaxis |
| Zdroj: | American Journal of Forensic Medicine & Pathology. 40:351-355 |
| ISSN: | 1533-404X 0195-7910 |
| Popis: | Postmortem tryptase is a useful biochemical test to aid the diagnosis of anaphylaxis. Multiple perimortem and postmortem factors have been documented to cause an elevation in postmortem tryptase level. One factor that was recently recognized to have an impact on postmortem tryptase level is correct sampling technique. A recent study recommended aspirating blood samples from a clamped femoral/external iliac vein to be used for reliable postmortem tryptase analysis. This study sampled 120 consecutive nonanaphylactic deaths in which all the peripheral bloods were sampled as recommended. Postmortem interval, resuscitation, different nonanaphylactic causes of death, sex, and age did not show any statistical significant relation to postmortem tryptase level in Student t test, Pearson correlation, and univariate and multivariate analyses. The mean (SD) postmortem tryptase level was 8.4 (5.2) μg/L (minimum, 1.0 μg/L; maximum, 36.1 μg/L; median, 7.3 μg/L). Using nonparametric methods, the postmortem tryptase reference range in nonanaphylactic death was established as |
| Databáze: | OpenAIRE |
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