Effect of Sotalol in the prevention of atrial fibrillation following coronary artery bypass grafting

Autor: Kaoru Matsuura, Keiichi Ishida, Yoshiharu Takahara, Yoshio Sudo
Rok vydání: 2001
Předmět:
Zdroj: The Japanese Journal of Thoracic and Cardiovascular Surgery. 49:614-617
ISSN: 1863-2092
1344-4964
DOI: 10.1007/bf02916225
Popis: Objective: We assessed the efficacy of postoperatively administered oral Sotalol in preventing the occurrence of postoperative atrial fibrillation.Methods: Subjects were 80 consecutive patients undergoing coronary artery bypass grafting (CABG) randomized alternately into a Sotalol group (40 patients) administered 80 mg of oral Sotalol daily starting on the postoperative day 1 and continued for 14 days, and a control group (40 patients) matched for age and gender.Results: The incidence of postoperative atrial fibrillation (21 patients) was significantly lower in the Sotalol group (6/40 patients; 15%) than in controls (15/40; 37.5%) (p
Databáze: OpenAIRE