Langerhans cell hyperplasia of the skin mimicking Langerhans cell histiocytosis: a report of two cases in children not associated with scabies
| Autor: | Alicia Rositto, Ana Garone, Ricardo Drut, Carlota Gómez Peral |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Pathology medicine.medical_specialty Langerhans cell Skin Diseases Pathology and Forensic Medicine Diagnosis Differential Scabies Langerhans cell histiocytosis medicine Humans Child Hyperplasia business.industry General Medicine medicine.disease Dermatology Histiocytosis Histiocytosis Langerhans-Cell medicine.anatomical_structure Langerhans Cells Pediatrics Perinatology and Child Health Female Differential diagnosis Spongiotic dermatitis business Contact dermatitis |
| Zdroj: | Fetal and pediatric pathology. 29(4) |
| ISSN: | 1551-3823 |
| Popis: | Langerhans cells histiocytosis (LCH) affecting the skin most commonly has clinical and histopathologic diagnostic features. We are reporting two examples of Langerhans cell (LC) hyperplasia recognized in the skin biopsies of two children initially interpreted as LCH. The first was an 8-year-old boy finally interpreted as having an atypical type of contact dermatitis, while the second, an 8-year-old girl, was assumed to have Pytiriasis lichenoides et varioliformis acuta. None showed evidences of scabies. Both presented spongiotic dermatitis with numerous CD1a+ cells. As more cases of LC hyperplasia are recognized, new details emerge helping in the differential diagnosis. Strict clinical-pathologic correlation is suggested in order to avoid misdiagnosis. |
| Databáze: | OpenAIRE |
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