Merocel versus Nasopore for nasal packing: a meta-analysis of randomized controlled trials

Autor: Changping Cai, Shili Wang, Jianzhang Wang
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Nasal cavity
Adhesion (medicine)
lcsh:Medicine
Mucous membrane of nose
Cochrane Library
law.invention
Randomized controlled trial
law
Nasal septum
Medicine and Health Sciences
lcsh:Science
Randomized Controlled Trials as Topic
Multidisciplinary
medicine.anatomical_structure
Research Design
Patient Satisfaction
Physical Sciences
Statistics (Mathematics)
Research Article
Biotechnology
medicine.medical_specialty
Clinical Research Design
Materials Science
Nasal Surgical Procedures
Surgical and Invasive Medical Procedures
Biostatistics
Research and Analysis Methods
Biomaterials
Patient satisfaction
Formaldehyde
medicine
otorhinolaryngologic diseases
Humans
Statistical Methods
Nasal Septum
Wound Healing
business.industry
lcsh:R
Biology and Life Sciences
Rhinology
medicine.disease
Bandages
Surgery
Otorhinolaryngology
Polyvinyl Alcohol
Nasal Diseases
lcsh:Q
business
Nasal concha
Mathematics
Meta-Analysis
Zdroj: PLoS ONE, Vol 9, Iss 4, p e93959 (2014)
PLoS ONE
ISSN: 1932-6203
Popis: OBJECTIVE: To compare the clinical outcomes, including efficacy and complications, of Merocel versus Nasopore as a nasal packing material after nasal surgery. METHODS: Relevant randomized controlled trials were identified from electronic databases (The Cochrane Library, PubMed, EMBASE, China National Knowledge Infrastructure and Chinese Biomedical Database). Conference proceedings and references from identified trials and review articles were also searched. Outcome measures were pain during nasal packing, pain and bleeding upon packing removal, pressure sensation, nasal blockage, formation of synechiae, mucosal healing, and patients' general satisfaction. RESULTS: Seven randomized controlled trials met criteria for analysis. Compared with Merocel, Nasopore significantly reduced patients' subjective symptoms including in situ pain (pain experienced while packing is in place), nasal pressure, pain and bleeding during packing removal, and increased patients' general satisfaction with nasal packing. There were no significant differences in nasal obstruction, adhesion and mucosal healing between the Merocel and Nasopore groups. CONCLUSIONS: Preliminary evidence suggests that Nasopore may be superior to Merocel as a nasal packing material with regard to in situ pain, pain and bleeding upon removal, pressure, and general satisfaction and does not differ from Merocel in terms of nasal obstruction, tissue adhesion, and long-term mucosal healing.
Databáze: OpenAIRE
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