| Autor: |
Silvia Regina Manfredi, Edgar Ferreira da Cruz, Maria Eugênia Fernandes Canziani, José Tarcísio Giffoni de Carvalho, Maria Aparecida Dalboni, Aline Trevisan Peres, Nadia K. Guimaraes-Souza, Marcelo Costa Batista, Miguel Cendoroglo, Beata Marie Redublo Quinto, Caren Cristina Grabulosa |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
ISRN Oxidative Medicine. 2014:1-7 |
| ISSN: |
2314-6400 |
| Popis: |
This study showed that indoxyl sulfate, an uremic toxin present in the serum of patients with chronic kidney disease, increases oxidative stress and apoptosis in human neutrophils and reduces the production of monocyte chemoattractant protein-1 (MCP-1) by peripheral blood mononuclear cell (PBMC). It is possible that these effects caused by this toxin contribute to vascular injury of the endothelium and decreased response to infectious insults, respectively. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
