| Autor: |
Sara, Mucherino, Manuela, Casula, Federica, Galimberti, Ilaria, Guarino, Elena, Olmastroni, Elena, Tragni, Valentina, Orlando, Enrica, Menditto, On Behalf Of The Edu Re Drug Group |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
International journal of environmental research and public health. 19(11) |
| ISSN: |
1660-4601 |
| Popis: |
Potentially inappropriate prescribing (PIP) is associated with an increased risk of adverse drug reactions, recognized as a determinant of adherence and increased healthcare costs. The study’s aim was to explore and compare the results of interventions to reduce PIP and its impact on avoidable healthcare costs. A systematic literature review was conducted according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement guidelines. PubMed and Embase were queried until February 2021. Inclusion criteria followed the PICO model: older patients receiving PIP; Interventions aimed at health professionals, structures, and patients; no/any intervention as a comparator; postintervention costs variations as outcomes. The search strategy produced 274 potentially relevant publications, of which 18 articles met inclusion criteria. Two subgroups were analyzed according to the study design: observational studies assessing PIP frequency and related-avoidable costs (n = 10) and trials, including specific intervention and related outcomes in terms of postintervention effectiveness and avoided costs (n = 8). PIP prevalence ranged from 21 to 79%. Few educational interventions carried out to reduce PIP prevalence and avoidable costs resulted in a slowly improving prescribing practice but not cost effective. Implementing cost-effective strategies for reducing PIP and clinical and economic implications is fundamental to reducing health systems’ PIP burden. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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