Recommendations on the effect of antidiabetic drugs in bone
| Autor: | Esteban Jódar-Gimeno, Rebeca Reyes-García, Pedro Rozas-Moreno, Mariela Varsavsky, María Cortés-Berdonces, Inés Luque-Fernández, Manuel Muñoz-Torres |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Drug medicine.medical_specialty media_common.quotation_subject Osteoporosis MEDLINE Dentistry 030209 endocrinology & metabolism Bone fragility Bone remodeling 03 medical and health sciences 0302 clinical medicine Glucagon-Like Peptide 1 Humans Hypoglycemic Agents Insulin Medicine 030212 general & internal medicine Bone Resorption Intensive care medicine Sodium-Glucose Transporter 2 Inhibitors Aged Randomized Controlled Trials as Topic media_common Bone mineral Dipeptidyl-Peptidase IV Inhibitors business.industry Contraindications Drug Antidiabetic treatment Middle Aged medicine.disease Metformin Quality of evidence Fractures Spontaneous Sulfonylurea Compounds Diabetes Mellitus Type 2 Female Thiazolidinediones Bone Remodeling business |
| Zdroj: | Endocrinología, Diabetes y Nutrición (English ed.). 64:1-6 |
| ISSN: | 2530-0180 |
| DOI: | 10.1016/j.endien.2016.11.002 |
| Popis: | Objective To provide recommendations on the effect of antidiabetic drugs on bone fragility to help select the most adequate antidiabetic treatment, especially in diabetic patients with high risk of fracture. Participants Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology. Methods The GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) was used to establish both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the following terms associated to the name of each antidiabetic drug: AND “osteoporosis”, “fractures”, “bone mineral density”, “bone markers”, “calciotropic hormones”. Papers in English with publication date before 30 April 2016 were reviewed. Recommendations were jointly discussed by the Working Group. Conclusions The document summaries the data on the potential effects of antidiabetic drugs on bone metabolism and fracture risk. |
| Databáze: | OpenAIRE |
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