Phenylvaleric Acid and Flavonoid Glycosides from Polygonum salicifolium
| Autor: | Otto Sticher, Ayşe Kuruüzüm, Peter Rüedi, Ihsan Calis, L. Ömür Demirezer, and Walter Ganci |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Polygonum
Spectrophotometry Infrared Turkey Stereochemistry Molecular Sequence Data Flavonoid Pharmaceutical Science Hyperoside Pharmacognosy Methylation Analytical Chemistry chemistry.chemical_compound Enzymatic hydrolysis Spectroscopy Fourier Transform Infrared Drug Discovery Glycosides Pentanoic Acids Flavonoids Pharmacology chemistry.chemical_classification Plants Medicinal biology Hydrolysis Organic Chemistry Glycoside Dihydrochalcone biology.organism_classification Polygonaceae Carbohydrate Sequence Complementary and alternative medicine chemistry Molecular Medicine Spectrophotometry Ultraviolet Astragalin |
| Zdroj: | Journal of Natural Products. 62:1101-1105 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np9900674 |
| Popis: | (3R)-O-beta-D-Glucopyranosyloxy-5-phenylvaleric acid (1), (3R)-O-beta-D-glucopyranosyloxy-5-phenylvaleric acid n-butyl ester (2), and a new dihydrochalcone diglycoside 4'-O-[beta-D-glucopyranosyl-(1--6)-glucopyranosyl]oxy-2'-hydroxy-3', 6'-dimethoxydihydrochalcone (3), together with six known flavonoid glycosides [kaempferol-3-O-beta-D-glucopyranoside (= astragalin) (4), kaempferol-3-O-beta-D-galactopyranoside (5), quercetin-3-O-beta-D-glucopyranoside (= isoquercitrin) (6), quercetin-3-O-beta-D-galactopyranoside (= hyperoside) (7), quercetin-3-O-(2''-O-galloyl)-beta-D-glucopyranoside (8), and quercetin-3-O-beta-D-glucuronopyranoside (9)] were isolated from the aerial parts of Polygonum salicifolium. The structure elucidation of the isolated compounds was performed by spectroscopic (UV, IR, ESI-MS, 1D- and 2D-NMR), chemical (methylation, enzymatic hydrolysis, partial synthesis), and chromatographic methods (HPLC, Chiralcel OD). The flavonoid glycosides (4-9) demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays. |
| Databáze: | OpenAIRE |
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