Radioimmunoscintigraphy with technetium-99m-labelled monoclonal antibody, SM3, in gynaecological cancer

Autor:	M. Granowska, K.E. Britton, S.J. Mather, D.G. Lowe, D. Ellison, J. Bomanji, J. Burchell, J. Taylor-Papadimitriou, C.R. Hudson, J.H. Shepherd
Rok vydání:	1993
Předmět:	Adult Ovarian Neoplasms Radioimmunodetection Genital Neoplasms Female Cystadenocarcinoma Humans Technetium Radiology Nuclear Medicine and imaging Female General Medicine Middle Aged Sensitivity and Specificity Aged
Zdroj:	European journal of nuclear medicine. 20(6)
ISSN:	0340-6997
Popis:	Radioimmunoscintigraphy (RIS) with technetium-99m labelled SM3, a monoclonal antibody reacting with a polymorphic epithelial mucin glycoprotein core antigen, is evaluated. No adverse effects or thyroid uptake were observed. Studies in 45 patients (one twice) had a sensitivity for gynaecological malignancy of 100% (35/35) and a specificity of 73% (8/11), giving an overall accuracy of 93% (43/46). These results have led to the routine adoption of 99mTc RIS in the management of patients suspected of or having primary or recurrent gynaecological cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0d050deb6df9b7ed77ac3a11b09774 https://pubmed.ncbi.nlm.nih.gov/8339731 Zobrazit plný text záznamu Full text from SpringerLink