A Dictyostelium morphogen that is essential for stalk cell formation is generated by a subpopulation of prestalk cells
| Autor: | S.M. Robbins, Linda Kwong, J. Daniel, Gerald Weeks, Y.J. Xie |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
biology
fungi Stalk cell differentiation Cell formation Gene Expression biology.organism_classification Blotting Northern behavioral disciplines and activities Dictyostelium humanities Cell biology body regions Genes Pentanones Gene expression Botany Stalk Cell RNA Messenger Molecular Biology Gene Developmental Biology Morphogen Cell region |
| Zdroj: | Development (Cambridge, England). 110(1) |
| ISSN: | 0950-1991 |
| Popis: | The stalk cell differentiation inducing factor (DIF) has the properties required of a morphogen responsible for pattern regulation during the pseudoplasmodial stage of Dictyostelium development. It induces prestalk cell formation and inhibits prespore cell formation, but there is as yet no strong evidence for a morphogenetic gradient of DIF. We have measured DIF accumulation by monolayers of isolated prestalk and prespore cells in an attempt to provide evidence for such a gradient. DIF is accumulated in the largest quantities by a subpopu lation of prestalk cells that specifically express the DIF-inducible genes pDd56 and pDd26. Since it has been shown recently that cells that express pDd56 are localized in the central core of the prestalk cell region of the pseudoplasmodia, our current results suggest a morphogenetic gradient generated by this region. |
| Databáze: | OpenAIRE |
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