Radiotherapy in the GHSG HD 16 and HD 17 trials – quality assurance and dosimetric analysis for Hodgkin lymphoma in the modern era

Autor: Oertel, Michael, Hering, Dominik Alexander, Nacke, Nina, Kittel, Christopher, Kröger, Kai Jannes, Kriz, Jan, Fuchs, Michael, Baues, Christian Manfred, Vordermark, Dirk, Engenhart, Rita, Herfarth, Klaus, Lukas, Peter, Schmidberger, Heinz, Marnitz-Schulze, Simone, Borchmann, Peter, Engert, Andreas, Haverkamp, Uwe, Eich, Hans-Theodor
Přispěvatelé: Universitäts- und Landesbibliothek Münster
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Popis: Introduction: Radiotherapy (RT) is an integral part of treatment concepts for early-stage Hodgkin lymphoma. The following analysis reports on RT-quality in the recent HD16 and 17 trials of the German Hodgkin Study Group (GHSG). Methods: All RT-plans of involved-node RT (INRT) in HD 17 were requested for analysis, along with 100 and 50 involved-field RT (IFRT) plans in HD 16 and 17, respectively. A structured assessment regarding field design and protocol adherence was performed by the reference radiation oncology panel of the GHSG. Results: Overall, 100 (HD 16) and 176 (HD 17) patients were eligible for analysis. In HD 16, 84 % of RT series were evaluated as correct, with significant improvement compared to the predecessor studies (p< 0.001). In HD 17, 76.1 % of INRT-cases revealed a correct RT design compared to 69.1 % of IFRT-cases, which was superior to prior studies (p
Databáze: OpenAIRE