Universal screening for latent and active tuberculosis (TB) in asylum seeking children, Bochum and Hamburg, Germany, September 2015 to November 2016
| Autor: | Ulf Schulze-Sturm, Robin Kobbe, Isa Auer, Maya Mueller-Hermelink, Frank Ahrens, Folke Brinkmann, Benedikt Methling, Cornelius Rau |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Tuberculosis Epidemiology Refugee Interferon gamma release assay Tuberculin Asymptomatic 03 medical and health sciences 0302 clinical medicine children Latent Tuberculosis Germany Virology Prevalence medicine Humans 030212 general & internal medicine Child Disease burden public health policy Refugees Travel Syria Tuberculin Test business.industry Incidence Incidence (epidemiology) Afghanistan Public Health Environmental and Occupational Health Infant Health sciences medicine.disease 030228 respiratory system Child Preschool surveillance Female medicine.symptom business Asylum seeker Delivery of Health Care Interferon-gamma Release Tests Research Article |
| Zdroj: | Mueller-Hermelink, M, Kobbe, R, Methling, B, Rau, C, Schulze-Sturm, U, Auer, I, Ahrens, F & Brinkmann, F 2018, ' Universal screening for latent and active tuberculosis (TB) in asylum seeking children, Bochum and hamburg, Germany, September 2015 to November 2016 ', Eurosurveillance, vol. 23, no. 12, 17-00536, pp. 4-9 . https://doi.org/10.2807/1560-7917.ES.2018.23.12.17-00536 Eurosurveillance |
| ISSN: | 1560-7917 |
| DOI: | 10.2807/1560-7917.es.2018.23.12.17-00536 |
| Popis: | Background In Germany, the incidence of tuberculosis (TB) in children has been on the rise since 2009. High numbers of foreign-born asylum seekers have contributed considerably to the disease burden. Therefore, effective screening strategies for latent TB infection (LTBI) and active TB in asylum seeking children are needed. Aim: Our aim was to investigate the prevalence of LTBI and active TB in asylum seeking children up to 15 years of age in two geographic regions in Germany. Methods: Screening for TB was performed in children in asylum seeker reception centres by tuberculin skin test (TST) or interferon gamma release assay (IGRA). Children with positive results were evaluated for active TB. Additionally, country of origin, sex, travel time, TB symptoms, TB contact and Bacille Calmette-Guérin (BCG) vaccination status were registered. Results: Of 968 screened children 66 (6.8%) had TB infection (58 LTBI, 8 active TB). LTBI prevalence was similar in children from high (Afghanistan) and low (Syria) incidence countries (8.7% vs 6.4%). There were no differences regarding sex, age or travel time between infected and non-infected children. Children under the age of 6 years were at higher risk of progression to active TB (19% vs 2% respectively, p=0,07). Most children (7/8) with active TB were asymptomatic at the time of diagnosis. None of the children had been knowingly exposed to TB. Conclusions: Asylum seeking children from high and low incidence countries are both at risk of developing LTBI or active TB. Universal TB screening for all asylum seeking children should be considered. |
| Databáze: | OpenAIRE |
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