Synthesis of the Scalarane Sesterterpenoid 16-deacetoxy-12-epi-scalarafuranacetate

Autor:	Bu-Bing Zeng, Jiangmeng Ren, Xi-Bo Chen, Jing Wang, Si-Kai Hua, Qian-Jia Yuan
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Sesterterpenes Natural product Molecular Structure Chemistry Stereochemistry Organic Chemistry Officinalis Stereoisomerism Stereoselectivity Diterpenes
Zdroj:	The Journal of Organic Chemistry. 76:7216-7221
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo2008127
Popis:	The marine natural product 16-deacetoxy-12-epi-scalarafuranacetate, isolated from Spongua officinalis , was synthesized in 18 linear steps, starting from (-)-sclareol, with high stereoselectivity and an overall yield of 6.1%. The intermediate 16-deacetoxy-12-epi-scalarafuran could be easily transformed into a series of natural scalarane sesterterpenoids in a few steps.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df63227cf7230d18d506dbf0b4ad07b https://doi.org/10.1021/jo2008127 Zobrazit plný text záznamu