The burden of central line-associated bloodstream infections in children with medical complexity
| Autor: | Lucilla Ravà, Michaela Carletti, Daniela Perrotta, Barbara Lucignano, Andrea Smarrazzo, Alessandro Crocoli, Francesco De Sanctis, Marta Ciofi Degli Atti, Riccardo Drago, Caterina Geremia, Maria Antonietta De Ioris, Alessia Scarselli, Marcella Aversa, Andrea Guerricchio, Andrea Campana |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatric intensive care unit
Central line medicine.medical_specialty business.industry medicine.medical_treatment 030501 epidemiology Gastrostomy 03 medical and health sciences 0302 clinical medicine Nephrology Intensive care Jejunostomy Medicine Surgery 030212 general & internal medicine 0305 other medical science business Intensive care medicine |
| Zdroj: | The journal of vascular access. |
| ISSN: | 1724-6032 |
| Popis: | Background: Central line-associated bloodstream infections (CLABSI) are significant cause of complications in pediatric intensive care units (PICUs). An emerging challenge are CLABSIs in children with medical complexity (CMC) admitted to PICU. CMC are patients with chronic conditions with or without neurological impairment needing for tracheostomy and/or home mechanical or non-invasive ventilation and/or gastrostomy/jejunostomy. We evaluate CLABSI incidence in a PICU with high prevalence of CMC. Methods: This was a retrospective study in the PICU of the Bambino Gesù Children Hospital from January 2017 to December 2020. The medical records were reviewed and demographic, clinical and microbiological data were extracted. CLABSI were defined according to the Center for Disease Control and Prevention’s National Healthcare Safety Networks (NHSN) surveillance. Results: A total of 101 children with 125 central lines (CLs) were included; 79/101 (78%) patients were CMC and 50/101 (50%) had a thracheostomy. CLABSI incidence was 2.75/1000 CL-days (9 cases/3269 CL-days); incidence was 0 in patients without underling conditions and 3.14/1000 in CMC ( p Conclusions: A target 0% CLABSI was possible in critically ill children without underling condition while a high incidence was reported in CMC and sustained by a peculiar CLABSI ecology. This ecology should be considered when a CLABSI was suspected in CMC for prompt antibiotics stewardship. |
| Databáze: | OpenAIRE |
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