Resistance to Organophosphorus and Pyrethroid Insecticides in Culex pipiens (Diptera: Culicidae) from Tunisia

Autor: Nicole Pasteur, Z. Ben Ali-Haouas, Maïté Marquine, H. Ben Cheikh
Přispěvatelé: Laboratoire de Génétique, Faculté de Médecine de Monastir, Université de Monastir - University of Monastir (UM), Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche pour le développement [IRD] : UR226
Rok vydání: 1998
Předmět:
0106 biological sciences
Insecticides
Veterinary medicine
Genes
Insect
01 natural sciences
Toxicology
chemistry.chemical_compound
0302 clinical medicine
Gene Frequency
Pyrethrins
education.field_of_study
Pyrethroid
Geography
biology
insensitive acetylcholinesterase
Organophosphate
insecticide resistance
3. Good health
Culex
Infectious Diseases
Chlorpyrifos
Temefos
medicine.drug
Tunisia
Pesticide resistance
Genotype
030231 tropical medicine
Population
Propoxur
Culex pipiens pipiens
esterases
03 medical and health sciences
parasitic diseases
Culex pipiens
[SDE.BE.EVO]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.evo
medicine
Animals
education
Alleles
Permethrin
Polymorphism
Genetic
General Veterinary
biology.organism_classification
010602 entomology
chemistry
Insect Science
Parasitology
[SDE.BE]Environmental Sciences/Biodiversity and Ecology
gene flow
Zdroj: Journal of Medical Entomology
Journal of Medical Entomology, Entomological Society of America, 1998, 35 (3), pp.251-260. ⟨10.1093/jmedent/35.3.251⟩
Journal of Medical Entomology, Entomological Society of America, 1998, 35 (3), pp.251-260
ISSN: 1938-2928
0022-2585
DOI: 10.1093/jmedent/35.3.251
Popis: International audience; Resistance to the organophosphates temephos and chlorpyrifos, the carbamate propoxur, the pyrethroid permethrin, and the organochloride DDT was investigated in Tunisian populations of Culex pipiens pipiens (L.) collected between 1990 and 1996. Resistance to temephos was uniformly low, reaching 10-fold in the most resistant population. In contrast, resistance to chlorpyrifos was highly variable, reaching the highest level (>10,000-fold) recorded worldwide. The chlorpyrifos-resistant populations also were highly resistant to propoxur. Some populations also showed high resistance to permethrin (up to 5,000-fold) and moderate resistance to DDT (approximate to 20-fold). Bioassays conducted in the presence of synergists showed that increased detoxification had only a minor role in resistance, although several over-produced esterases known to be involved in organophosphate resistance were detected. To better understand the factors influencing the distribution of resistance in Tunisia, the polymorphism of genes involved in organophosphate resistance (i.e., over-produced esterases and insensitive acetylcholinesterase) was investigated in relation to the genetic structure of populations studied by analyzing the electrophoretic polymorphism of "neutral" genes. Over the area studied, and despite a high level of gene flow, resistance genes showed a patchy distribution. Results are discussed in relation to the selection pressure caused by insecticide treatments.
Databáze: OpenAIRE
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