Curative surgery for gastric cancer: Study of 166 consecutive patients
| Autor: | Costa Cs, Bettencourt A, de Almeida Jm, de Almeida Jc |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate analysis medicine.medical_treatment Gastroenterology Gastrectomy Stomach Neoplasms Internal medicine medicine Humans Lymph node Survival analysis Aged Aged 80 and over business.industry Mortality rate Univariate Middle Aged Surgery Survival Rate medicine.anatomical_structure Lymph Node Excision Female Lymphadenectomy business Abdominal surgery |
| Zdroj: | World Journal of Surgery. 18:889-894 |
| ISSN: | 1432-2323 0364-2313 |
| DOI: | 10.1007/bf00299097 |
| Popis: | From January 1980 to December 1991 we operated on 295 patients with a gastric carcinoma. In 166 cases (56.3%) surgery was performed with curative intent. In 93 patients (56%) a subtotal gastrectomy was performed, and in 73 cases (44%) a total gastrectomy. In all the cases a D-2 type lymphadenectomy was used. The global morbidity rate was 23%, and in-hospital mortality was 3.6%. The morbidity and mortality rates of these two operations were statistically different. Global 5-year survival estimate for the whole series is 61.3%. Univariate and multivariate analysis according to T and N (TNM classification), the number of positive nodes resected, and the relation of positive per resected nodes, revealed statistically different outcomes. This kind of quantitative classification allowed identification of high risk groups irrespective of site of nodal involvement. Tumors classified as intestinal or diffuse type by the Lauren classification had similar survival curves and 5-year survival estimates (p = 0.834). By univariate and multivariate analysis this classification did not reveal a prognostic value in this group of patients. In our opinion, tumor penetration and lymph node involvement are at present the most reliable prognostic factors available. |
| Databáze: | OpenAIRE |
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