Photoacoustic imaging of fresh human surgically and endoscopically resected gastrointestinal specimens

Autor: Dai Murakoshi, Shinpei Okawa, Takeshi Kuwata, Kaku Irisawa, Tomonori Yano, Tomohiro Mitsui, Satoshi Ozawa, Miya Ishihara, Atsushi Ochiai, Toshihiko Omori, Takeo Fujita, Tatsunori Minamide, Masaaki Ito, Hiroaki Ikematsu, Takahiro Kinoshita
Rok vydání: 2021
Předmět:
Zdroj: DEN open. 2(1)
ISSN: 2692-4609
Popis: Photoacoustic (PA) imaging is a novel noninvasive technique that offers high-contrast tomographic imaging with ultrasound-like resolution at depths of centimeters, enabling visualization of deep small vessels. The aim of this pilot study was to survey the characteristics of deep vessel networks in the mucosa of neoplastic gastrointestinal (GI) lesions using PA imaging.Specimens of patients who had undergone surgical and endoscopic resection for GI lesions were included in this study. The PA/ultrasound imaging system for clinical research is characterized by a technology that can superimpose a PA image over an ultrasound image. Three-dimensional PA images were acquired for the resected specimen before fixation. The stomach and colon of live pigs were incised, and the walls were scanned from the mucosa.A total of 32 specimens (nine esophageal, 12 gastric, 11 colorectal) were scanned. The pathological diagnoses were adenomas (Our study confirmed that the deep vessel networks of neoplastic GI lesions were visible by PA imaging.
Databáze: OpenAIRE