Alveolar hemorrhage and kidney disease: Characteristics and therapy
| Autor: | Zohra El Ati, Smaoui Wided, Dorra Ben Aich, Somaya Beji, Zouaghi Karim, Krid Madiha, Lilia Ben Fatma, Hedi Ben Maiz, Fatma Ben Moussa, Rais Lamia |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Lung Diseases Male medicine.medical_specialty lcsh:Medicine Hemorrhage Gastroenterology Young Adult Antiphospholipid syndrome Internal medicine medicine Humans Aged Retrospective Studies medicine.diagnostic_test business.industry lcsh:R Diffuse alveolar hemorrhage General Medicine Middle Aged medicine.disease Cryoglobulinemia Surgery Pulmonary Alveoli Bronchoalveolar lavage Methylprednisolone Female Kidney Diseases Vasculitis Microscopic polyangiitis business Kidney disease medicine.drug |
| Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 24, Iss 4, Pp 743-750 (2013) |
| ISSN: | 1319-2442 |
| Popis: | Anti-neutrophil cytoplasmic antibody-associated vasculitis and Goodpasture's glomerular basement membrane disease are the most common causes of diffuse alveolar hemorrhage, a life-threatening disease. Systemic lupus erythematosus and the antiphospholipid syndrome are also causes of alveolar hemorrhage. We retrospectively reviewed 15 cases of diffuse alveolar hemorrhage (DAH) associated with renal diseases. Diagnosis of DAH was based on the presence of bloody bronchoalveolar lavage fluid. There were three men and 12 women, with a mean age of 50.5 years (extremes: 24-74 years). Proteinuria and hematuria were observed, respectively, in 15 and 14 cases. Six patients revealed arterial hypertension. Crescentic glomerulonephritis was diagnosed with kidney biopsies in ten cases. The etiology of renal disease was microscopic polyangiitis (MPA) in seven cases, Wegener disease in four cases, systemic lupus erythematous in one case, cryoglobulinemia in one case, myeloma in one case and propyl-thiouracil-induced MPA in one case. Hemoptysis occurred in 14 cases. The mean serum level of hemoglobin was 7.1 g/dL (5.1-10 g/dL). The mean serum creatinine concentration was 7.07 mg/dL (2.4-13.7 mg/dL). Gas exchange was severely compromised, with an oxygenation index |
| Databáze: | OpenAIRE |
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