Adherence to therapeutic and diagnostic recommendations in patients with femur fracture and at risk of re-fracture or death: Results of an analysis of administrative databases
| Autor: | C Cagnoni, Salvatore Minisola, Chiara Veronesi, L. Degli Esposti, Luigi Sinigaglia, Maurizio Rossini, Stefano Buda, Chiara Magliaro, Silvano Adami |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
pharmacoutilization
Databases Factual refracture lcsh:Medicine Comorbidity Strontium ranelate Recurrence Risk Factors Vitamin D Diagnostic Techniques and Procedures Health Services Administration Osteoporosis Postmenopausal Aged 80 and over Hip fracture Bone Density Conservation Agents Diphosphonates Health Services Prescriptions hip fracture Practice Guidelines as Topic Female Guideline Adherence Medical Record Linkage femur fracture treatment adherence pharmacoutilization hip fracture osteoporosis refracture death medicine.drug Risk lcsh:Internal medicine medicine.medical_specialty Thiophenes treatment adherence Drug Prescriptions Rheumatology Internal medicine death medicine Vitamin D and neurology Humans In patient Medical prescription osteoporosis lcsh:RC31-1245 Aged Retrospective Studies Femur fracture business.industry Hip Fractures lcsh:R Retrospective cohort study Bone fracture medicine.disease Drug Utilization Surgery Polypharmacy Calcium business |
| Zdroj: | Reumatismo, Vol 64, Iss 1, Pp 18-26 (2012) |
| Popis: | The aim of the present study was to evaluate the application into clinical practice of therapeutic and diagnostic recommendations for the prevention of bone re-fracture in postmenopausal women after an hospitalization for hip fracture in clinical practice and to assess the relationship between the application of diagnostic recommendations and re-fracture or death risk. A retrospective cohort analysis was conducted. All female patients, at least 65 years old, and with an hospitalization with main or secondary diagnosis of hip fracture during the period 1 January 2006 – 31 December 2008, were included. Besides demographic characteristics and comorbidities, drug treatment prescriptions related to bone fracture or supplementary with calcium or vitamin D and prescriptions of recommended laboratory and instrumental diagnostic tests (e.g. spine radiography), were analysed. A total of 5,636 patients were included in the study. The prescription of a drug treatment aimed to reduce the risk of re-fracture was found in 16.3% of patients, among them 76.3% (699 patients) used bisphosphonates only, 17.1% (157 patients) strontium ranelate only and 4.9% (45 patients) used more than one treatment during the observation period. Among the patients who did not receive drug treatment, 17.5% made use of only supplemental calcium and vitamin D. The remaining part of patients (69.1%) received no treatment. The prescription of at least one laboratory test of first and second level was performed, respectively, on 53.7% and 43.1% of included patients, whereas the prescription of at least one instrumental test of first and second level was performed, respectively, on 5.9% and 0.8%. Although it is established that the prescription of the recommended tests and appropriate drug treatment are significantly associated with reduced risk of re-fracture and death, today the application of these recommendations is reduced. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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