Histologic Evaluation of rhBMP-2 in an Extraction Site Model in the Esthetic Zone: A Series of 16 Cases Preparing for Implant Placement
| Autor: | Michael K. McGuire, Randy S. Demetter, E. Todd Scheyer, Brian L. Mealey, David I. Lipton, Blaine G. Calahan |
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| Rok vydání: | 2020 |
| Předmět: |
Bone Morphogenetic Protein 2
Dentistry Esthetics Dental Bone morphogenetic protein Bone morphogenetic protein 2 Osteogenesis Transforming Growth Factor beta Alveolar Process medicine Humans Dental Implants biology business.industry Alveolar process Mesenchymal stem cell Alveolar Ridge Augmentation Transforming growth factor beta Recombinant Proteins medicine.anatomical_structure Bone Morphogenetic Proteins biology.protein Periodontics Oral Surgery business Wound healing Transforming growth factor |
| Zdroj: | The International Journal of Periodontics & Restorative Dentistry. 40:171-179 |
| ISSN: | 0198-7569 |
| Popis: | Growth factors have been used in numerous oral applications to aid in bone formation after tooth extraction. Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-b superfamily and are involved in the differentiation of pluripotent mesenchymal cells, leading to new bone formation through osteoblastic induction. This study examined histologic wound healing following extraction and ridge preservation using recombinant human BMP-2 (rhBMP-2) and a collagen sponge. Formation of new vital bone was seen, suggesting that this material is a viable option for ridge preservation in preparation for implant placement. |
| Databáze: | OpenAIRE |
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