Additional file 1: of Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome

Autor: Hargreaves, Patrick, Daoudlarian, Douglas, Theron, Michel, Kolb, Fabrice, Young, Marianne Manchester, Reis, Bernhard, Tiaden, Andre, Bannert, Bettina, Kyburz, Diego, Manigold, Tobias
Rok vydání: 2019
DOI: 10.6084/m9.figshare.8957849.v1
Popis: Figure S1. Ex vivo effects of RO5459072. RO5459072 led to a dose-dependent p10 accumulation in B cells when compared to monocytes (A). In addition, 80 mM of RO5459072 led to significantly decreased CatS ratios in tear fluid, but not other biocompartments, of pSS after an incubation of 180 min (B, two-tailed t test, ** p
Databáze: OpenAIRE