CKD and Health-Related Quality of Life: The Korea National Health and Nutrition Examination Survey
| Autor: | Hae Hyuk Jung, Hyunjeong Baek, Ji In Park |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty National Health and Nutrition Examination Survey Cross-sectional study Population 030232 urology & nephrology Renal function urologic and male genital diseases 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine Republic of Korea medicine Humans 030212 general & internal medicine Renal Insufficiency Chronic education Aged Health related quality of life education.field_of_study Proteinuria business.industry Middle Aged medicine.disease Nutrition Surveys Cross-Sectional Studies Nephrology Physical therapy Quality of Life Female medicine.symptom business Kidney disease |
| Zdroj: | American journal of kidney diseases : the official journal of the National Kidney Foundation. 67(6) |
| ISSN: | 1523-6838 |
| Popis: | Background Quality of life is increasingly viewed as an important health outcome. However, the association of chronic kidney disease (CKD) and its severity with health-related quality of life is uncertain. Study Design Nationwide population-based cross-sectional study. Setting & Participants 46,676 adults participating in the Korea National Health and Nutrition Examination Survey (KNHANES) 2005 to 2013. Predictor CKD ascertained as dipstick-positive proteinuria or estimated glomerular filtration rate (eGFR) 2 . 5 eGFR categories of CKD were compared: ≥90 (with proteinuria), 60 to 89 (with proteinuria), 45 to 59, 30 to 44, and 2 . Outcomes The EQ-5D index for health status (range, 0 [death] to 1 [optimal health]). Results The total crude CKD prevalence estimate for adults 20 years or older in Korea was 5.5%. After adjustments for age, sex, risk factors, and comorbid conditions, the EQ-5D index was lower in those with versus without CKD, with mean differences of −0.004 (95% CI, −0.015 to 0.007), −0.016 (95% CI, −0.032 to −0.000), −0.020 (95% CI, −0.029 to −0.011), −0.052 (95% CI, −0.072 to −0.032), and −0.067 (95% CI, −0.101 to −0.032), respectively, for CKD eGFR categories of ≥90, 60 to 89, 45 to 59, 30 to 44, and 2 . In the subgroup of older (≥60 years) individuals, the adjusted mean difference in the EQ-5D index was lower in the CKD eGFR category of 60 to 89mL/min/1.73m 2 , but not in the eGFR category of 45 to 59mL/min/1.73m 2 , compared to non-CKD. Limitations The survey was conducted on noninstitutionalized civilians, and the chronicity of kidney disease was not verified. Caution is required if our results are applied to special settings and specific populations. Conclusions There was a graded but complex association between CKD and poor health-related quality of life in this large community-based population. |
| Databáze: | OpenAIRE |
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