QUANTITATIVE IN VITRO STUDIES ON STIMULATION OF MURINE HAEMOPOIETIC CELLS BY COLONY STIMULATING FACTOR
| Autor: | Gerrit J. van den Engh |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
medicine.medical_specialty
Erythrocytes Time Factors Placenta Bone Marrow Cells Cell Count Stimulation Urine Biology Mice Fetus Bone Marrow Pregnancy Internal medicine medicine Animals Humans Trypsin Cells Cultured Cell Aggregation Glycoproteins chemistry.chemical_classification Uterus Cell Biology General Medicine Fibroblasts Colony-stimulating factor Molecular biology Cell aggregation In vitro medicine.anatomical_structure Endocrinology chemistry Mechanism of action Female Bone marrow medicine.symptom Glycoprotein Ultracentrifugation |
| Zdroj: | Cell Proliferation. 7:537-548 |
| ISSN: | 1365-2184 0960-7722 |
| DOI: | 10.1111/j.1365-2184.1974.tb00437.x |
| Popis: | A new standardization method for Colony Stimulating Factor (CSF) is described and criteria are introduced which enables stimulating activity to be assessed independent of absolute colony numbers. With this method CSF preparations from different sources are compared and evidence is presented that suggests an identical mechanism of action for these substances. Data are presented on the increase in colony numbers that is induced by the addition of erythrocyte lysates to the cultures. The relationship between colony forming cells that are stimulated by CSF alone and cells stimulated by the combined action of CSF and erythrocyte lysate is discussed. |
| Databáze: | OpenAIRE |
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